OUR EXPERIENCE OF AUTOLOGOUS RETINAL TRANSPLANTATION IN A PATIENT WITH A GIANT MACULAR HOLE (CLINICAL CASE)

Authors

DOI:

https://doi.org/10.71110/ajo791020251703545561

Keywords:

vitreoretinal surgery, macula, giant macular hole, autologous retinal transplantation

Abstract

Purpose – to demonstrate our experience in the application of autologous retinal transplantation in a patient with a giant macular hole.

Material and methods

A 54-year-old patient presented with complaints of a significant decrease in visual acuity, difficulties in the perception of object shapes, and the presence of a central scotoma. Before surgery, the best corrected visual acuity was 0.02. Optical coherence tomography (OCT) revealed a giant macular hole with a diameter of 1248 micrometers. The patient underwent bimanual autologous retinal transplantation into the area of the giant macular hole using perfluorocarbon liquid, followed by tamponade with silicone oil.

Results

The performed bimanual autologous retinal transplantation in a giant macular hole with the use of perfluorocarbon liquid was successful both anatomically and functionally, as confirmed by objective examination data. This suggests that the technique can be effectively applied in the treatment of giant macular holes.

Perimetry of the macular zone demonstrated positive dynamics. On the first day after the surgery, the best corrected visual acuity improved to 0.3. One month later, the ophthalmoscopic picture remained stable without any signs of autograft dislocation. OCT confirmed persistent attachment of the flap, and the perimetry results maintained positive dynamics. The best corrected visual acuity remained at the achieved level, indicating the high effectiveness of the method and a favorable prognosis for visual rehabilitation.

Conclusion

Experience with autologous retinal transplantation suggests that this method is effective in the treatment of giant macular holes, allowing significant improvement of both anatomical and functional outcomes.

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Published

2025-10-01

Issue

Section

CLINICAL CASES

How to Cite

[1]
Faizrakhmanov R.R. et al. 2025. OUR EXPERIENCE OF AUTOLOGOUS RETINAL TRANSPLANTATION IN A PATIENT WITH A GIANT MACULAR HOLE (CLINICAL CASE). The Azerbaijan Journal of Ophthalmology. 17, 54 (Oct. 2025), 55–61. DOI:https://doi.org/10.71110/ajo791020251703545561.
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