AKTİPOLUN TƏSİRİNDƏN SƏTHİ FORMALI HERPETİK KERATİTLİ XƏSTƏLƏRDƏ (KONYUNKTİVA YUYUNTUSUNDA) İNTERLEYKİN-6-NIN DƏYİŞMƏ DİNAMİKASI

Abstract

SUMMARY

The aim of the study was to compare the effect of actipol on interleukine-6 (IL-6) levels in patients with
herpetic keratitis.
Enzyme immunoassay was used to measure lacrimal fluid IL-6 levels in the actipol and acyclovir qroups before
and on 1,2, 3,4, 7 or 8 days after therapy and after clinical recovery in 30 patients with herpetic keratitits. A control
group comprised apparently healthy volunteers (n=13, 26 eyes) who used actipol instillations into the conjunctival
sac 4-5 times a day.
In the patients with superficial herpetic keratitis actipol was found to reduce and normalize tear IL-6 levels
while acyclovir failed to produce this effect. In the healthy individuals actipol did not affect IL-6 production in the
anterior segment of eye.