XRONİKİ BLEFARİT FONUNDA "QURU GÖZ SINDROMU" OLAN XƏSTƏLƏRİN MÜALİCƏSİNİN BİR SIRA ASPEKTLƏRİ
Açar sözlər:
chronic blepharitis, dry eye syndrome, corticosteroids, 0.05% cyclosporineXülasə
SUMMARY
Aim - to determine the effective treatment of blepharitis by clinical course characteristics in patients with DES developing on the background of chronic blepharitis based on clinical and laboratory findings.
Material and methods
The study included 48 patients aged 25-65 years with dry eye syndrome developed on the background of
chronic blepharitis. Depending on the treatment prescribed, the patients were divided into 2 groups: 25 patients (7
men and 18 women) (50 eyes) and 23 patients (7 men and 16 women) (46 eyes).
Results
Treatment of patients with group 1 includes lubricants and corticosteroids in a decreasing manner. In the 2nd
group, in addition to therapy, patients were administered 0.05% solution of cyclosporine (Depores, Vefa ila?)
twice a day for 3-4 months. The observation period ranged from 6 to 12 months. Patients underwent visometry,
pneumotonometry, biomicroscopy and ophthalmoscopy. With the help of additional methods, the state of the free
edge of the eyelids and excretory ducts of meibomian glands (biomicroscopy), eye surface (cytology), tear film
stability (Norn's test), tear production (Schirmer's test I), measurement of the tear meniscus were evaluated.
It was established that the frequency of development and severity of clinical manifestations of DES depend on
the nature of the secretion of meibomian glands, sex, age and complications of chronic blepharitis with chalagions.
Conclusion
So, prolonged use of a 0.05% solution of cyclosporine in combination with a corticosteroid and lubricant as a
combined anti-inflammatory treatment in patients with dry eye syndrome with chronic blepharitis has a positive
clinical result.